Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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cdh7aCdh7 protein; Cadherins are calcium-dependent cell adhesion proteins. (787 aa)    
Predicted Functional Partners:
sema6dl
Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D,-like.
      
 0.780
ctnnb1
Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...]
    
 0.677
ctnna2
Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system; Belongs to the vinculin/alpha-catenin family.
   
 0.632
ctnnb2
Catenin, beta 2.
    
 0.624
ctnnd1
Catenin (cadherin-associated protein), delta 1.
    
 0.603
fjx1
Four-jointed box kinase 1.
   
 0.540
ctnna1
Catenin (cadherin-associated protein), alpha 1.
   
 0.531
arvcfb
ARVCF delta catenin family member b.
    
 0.530
nalcn
Sodium leak channel, non-selective.
   
  
 0.517
ctnnd2a
Catenin (cadherin-associated protein), delta 2a.
    
 0.509
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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