STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pnocaPrepronociceptin a. (277 aa)    
Predicted Functional Partners:
oprl1
Opioid receptor-like protein Zf-orl; Belongs to the G-protein coupled receptor 1 family.
   
 0.996
pyyb
Peptide YYb.
     
 0.863
pdyn
Prodynorphin.
   
 
0.849
galn
Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1 (galr1a and galr1b) and GALR2 (galr2a and galr2b). This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion.
     
 0.832
pomca
Pro-opiomelanocortin protein.
     
 0.727
oprk1
Opioid receptor, kappa 1; Belongs to the G-protein coupled receptor 1 family.
   
 0.725
sst1.1
Somatostatin 1, tandem duplicate 1.
   
 
 0.721
penka
Proenkephalin a.
     
0.692
npb
Neuropeptide B.
     
 0.691
A2CEM5_DANRE
Si:ch211-145o7.3.
      
 0.674
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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