Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
glcci1aGlucocorticoid-induced 1a. (531 aa)    
Predicted Functional Partners:
FAM53C
LOC100002393 protein.
   
  
 0.808
zgc:92518
Zgc:92518.
      
 0.800
dusp19b
Dual-specificity phosphatase 19b.
      
 0.796
dcaf7
Ddb1 and cul4-associated factor 7.
    
 
 0.753
rnf169
E3 ubiquitin-protein ligase RNF169; Probable E3 ubiquitin-protein ligase that acts as a negative regulator of double-strand breaks (DSBs) repair following DNA damage.
   
  
 0.727
med25
Mediator of RNA polymerase II transcription subunit 25; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
      
 0.689
krcp
Kelch repeat-containing protein.
      
 0.686
calhm5.1
Calcium homeostasis modulator protein 5; Pore-forming subunit of a voltage-gated ion channel. Belongs to the CALHM family.
      
 0.600
csad
Cysteine sulfinic acid decarboxylase.
   
  
 0.570
p4htm
Prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum).
      
 0.567
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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