Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
rtn4rReticulon 4 receptor. (479 aa)    
Predicted Functional Partners:
ngfra
Nerve growth factor receptor a (TNFR superfamily, member 16).
    
 
 0.887
rtn4a
Reticulon.
    
 
 0.844
omgb
Oligodendrocyte myelin glycoprotein b.
    
 
 0.804
mag
Myelin-associated glycoprotein.
   
 0.745
lingo1b
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1-B; May play a role in regulating axonal regeneration and plasticity in the adult central nervous system.
  
 
0.744
smtnl1
Smoothelin-like 1.
      
 0.707
rtn4b
Reticulon.
   
 
 0.633
E7F2N2_DANRE
Aminopeptidase.
    
 
 0.597
E7F123_DANRE
Aminopeptidase.
    
 
 0.597
ANPEP
Aminopeptidase.
    
 
 0.582
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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