Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sult1st4Sulfotransferase; Belongs to the sulfotransferase 1 family. (304 aa)    
Predicted Functional Partners:
hsd17b8
FabG (Beta-ketoacyl-[acyl-carrier-protein] reductase, E. coli) like.
     
 0.614
hsd17b7
Hydroxysteroid (17-beta) dehydrogenase 7.
     
 0.605
hsd17b2
Hydroxysteroid (17-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.595
cyp3a65
Cytochrome P450, family 3, subfamily A, polypeptide 65; Belongs to the cytochrome P450 family.
   
 
  0.572
hsd20b2
20beta-hydroxysteroid dehydrogenase type 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
  0.561
cyp19a1a
Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.
     
  0.561
cyp1d1
Cytochrome P450, family 1, subfamily D, polypeptide 1; Belongs to the cytochrome P450 family.
   
 
 0.527
cyp1a
Cytochrome P450, family 1, subfamily A; Belongs to the cytochrome P450 family.
   
 
 0.527
akr1a1a
Aldo-keto reductase family 1 member A1-A; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosaccharides and bile acids. Acts as an aldehyde-detoxification enzyme (By similarity). Displays no reductase activity towards retinoids (By similarity).
   
 
 0.444
hsd17b1
Hydroxysteroid (17-beta) dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
  0.442
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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