Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prdm8PR domain-containing 8. (502 aa)    
Predicted Functional Partners:
prdm10
PR domain zinc finger protein 10; May be involved in transcriptional regulation.
    
 0.789
PRDM15
PR/SET domain 15.
    
 0.785
prdm4
PR domain-containing 4.
    
 0.782
prdm16
Si:ch211-263k4.2.
    
 0.781
bhlhe22
Basic helix-loop-helix family, member e22.
   
  
 0.759
prdm2b
PR domain-containing 2, with ZNF domain b.
      
 0.734
prdm5
PR domain-containing 5.
    
 0.697
prdm12b
PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily.
   
  
 0.695
setmar
SET domain and mariner transposase fusion protein.
    
 0.677
mecom
MDS1 and EVI1 complex locus.
    
 0.671
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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