STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmem9bTMEM9 domain family, member B. (196 aa)    
Predicted Functional Partners:
rnf141
RING finger protein 141.
      
 0.645
prcp
Prolylcarboxypeptidase (Angiotensinase c).
      
 0.645
actr3
Actin-related protein 3; Belongs to the actin family.
   
  
 0.644
acer3
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
      
 0.569
srgap1a
SLIT-ROBO Rho GTPase-activating protein 1a.
   
  
 0.566
tle5
TLE family member 5, transcriptional modulator.
      
 0.564
rnf216
Ring finger protein 216.
      
 0.551
srgap2
SLIT-ROBO Rho GTPase-activating protein 2; RAC1 GTPase activating protein (GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. May play a role in different aspects of neuronal morphogenesis and migration. This includes the biogenesis of neurites, where it could be required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. May also stimulate the branching of the leading process and negatively regulates neuron migration. In non-neuronal cells, it may also play a role in cell migration by reg [...]
   
  
 0.484
CCKBR
Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.480
trim2a
Tripartite motif-containing 2a.
      
 0.479
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.