Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sulf2bExtracellular sulfatase. (885 aa)    
Predicted Functional Partners:
tmed7
Transmembrane p24-trafficking protein 7.
      
 0.689
lrrc4bb
Leucine-rich repeat-containing 4Bb.
    
 
 0.686
wu:fb59d01
Wu:fb59d01.
      
 0.682
or129-1
Odorant receptor, family H, subfamily 129, member 1.
      
 0.681
rbm4.3
RNA-binding motif protein 4.3.
      
 0.662
naa25
N(alpha)-acetyltransferase 25, NatB auxiliary subunit.
      
 0.662
gusb
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.
  
 0.653
ier5l
Immediate early response gene 5-like protein; Belongs to the IER family.
   
  
 0.652
lrrc4.2
Leucine-rich repeat-containing 4.2.
    
 
 0.599
ildr1a
Immunoglobulin-like domain-containing receptor 1a.
      
 0.579
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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