STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppp4r2aSerine/threonine-protein phosphatase 4 regulatory subunit 2-A; Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4C); Belongs to the PPP4R2 family. (422 aa)    
Predicted Functional Partners:
smek1
Serine/threonine-protein phosphatase 4 regulatory subunit 3; Regulatory subunit of serine/threonine-protein phosphatase 4. Belongs to the SMEK family.
   
 0.953
ppp4r3b
Protein phosphatase 4, regulatory subunit 3B.
   
 0.940
ptpa
Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
   
 0.915
ppp4ca
Serine/threonine-protein phosphatase 4 catalytic subunit A; Protein phosphatase that regulates many processes such as microtubule organization at centrosomes; Belongs to the PPP phosphatase family. PP-4 (PP-X) subfamily.
   
 
 0.857
ppp4cb
Serine/threonine-protein phosphatase 4 catalytic subunit B; Protein phosphatase that regulates many processes such as microtubule organization at centrosomes; Belongs to the PPP phosphatase family. PP-4 (PP-X) subfamily.
   
 
 0.845
ppp3ca
Serine/threonine-protein phosphatase.
    
 0.741
ppp3cb
Serine/threonine-protein phosphatase.
    
 0.741
ppp3ccb
Serine/threonine-protein phosphatase.
    
 0.741
ppp3cca
Serine/threonine-protein phosphatase.
    
 0.741
supt5h
Transcription elongation factor SPT5; May function as a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II. Probably enhances transcriptional pausing at sites proximal to the promoter, which may facilitate the assembly of an elongation competent RNA polymerase II complex. Also acts to stimulate transcriptional elongation at low nucleotide concentrations. Regulation of transcriptional elongation by this protein is required for the expression of genes which control neuronal development. Belongs to the SPT [...]
    
 
 0.739
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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