node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aars1 | eprs1 | ENSDARP00000120649 | ENSDARP00000070224 | Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | Glutamyl-prolyl-tRNA synthetase. | 0.979 |
aars1 | iars1 | ENSDARP00000120649 | ENSDARP00000009149 | Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | Isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.961 |
aars1 | iars2 | ENSDARP00000120649 | ENSDARP00000064802 | Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | Isoleucyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.894 |
aars1 | nars1 | ENSDARP00000120649 | ENSDARP00000121524 | Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | Asparaginyl-tRNA synthetase. | 0.743 |
aars1 | sars1 | ENSDARP00000120649 | ENSDARP00000015775 | Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | Serine--tRNA ligase, cytoplasmic; Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser). Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec). In the nucleus, binds to the vegfa core promoter and prevents myc binding and transcriptional activation by myc. Thereby inhibits the production of vegfa and sprouting angiogenesis mediated by vegfa. Belongs t [...] | 0.914 |
aars1 | tars1 | ENSDARP00000120649 | ENSDARP00000036825 | Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | Threonyl-tRNA synthetase. | 0.935 |
aars1 | vars1 | ENSDARP00000120649 | ENSDARP00000142328 | Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | Valyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.951 |
aars1 | wars | ENSDARP00000120649 | ENSDARP00000136378 | Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | Tryptophanyl-tRNA synthetase. | 0.965 |
aars1 | yars1 | ENSDARP00000120649 | ENSDARP00000052125 | Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | Tyrosine--tRNA ligase, cytoplasmic; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). | 0.999 |
aars1 | yars2 | ENSDARP00000120649 | ENSDARP00000070911 | Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | Tyrosine--tRNA ligase. | 0.948 |
eprs1 | aars1 | ENSDARP00000070224 | ENSDARP00000120649 | Glutamyl-prolyl-tRNA synthetase. | Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. | 0.979 |
eprs1 | iars1 | ENSDARP00000070224 | ENSDARP00000009149 | Glutamyl-prolyl-tRNA synthetase. | Isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.999 |
eprs1 | iars2 | ENSDARP00000070224 | ENSDARP00000064802 | Glutamyl-prolyl-tRNA synthetase. | Isoleucyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.999 |
eprs1 | nars1 | ENSDARP00000070224 | ENSDARP00000121524 | Glutamyl-prolyl-tRNA synthetase. | Asparaginyl-tRNA synthetase. | 0.999 |
eprs1 | sars1 | ENSDARP00000070224 | ENSDARP00000015775 | Glutamyl-prolyl-tRNA synthetase. | Serine--tRNA ligase, cytoplasmic; Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser). Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec). In the nucleus, binds to the vegfa core promoter and prevents myc binding and transcriptional activation by myc. Thereby inhibits the production of vegfa and sprouting angiogenesis mediated by vegfa. Belongs t [...] | 0.967 |
eprs1 | tars1 | ENSDARP00000070224 | ENSDARP00000036825 | Glutamyl-prolyl-tRNA synthetase. | Threonyl-tRNA synthetase. | 0.974 |
eprs1 | vars1 | ENSDARP00000070224 | ENSDARP00000142328 | Glutamyl-prolyl-tRNA synthetase. | Valyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.999 |
eprs1 | wars | ENSDARP00000070224 | ENSDARP00000136378 | Glutamyl-prolyl-tRNA synthetase. | Tryptophanyl-tRNA synthetase. | 0.979 |
eprs1 | yars1 | ENSDARP00000070224 | ENSDARP00000052125 | Glutamyl-prolyl-tRNA synthetase. | Tyrosine--tRNA ligase, cytoplasmic; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). | 0.999 |
eprs1 | yars2 | ENSDARP00000070224 | ENSDARP00000070911 | Glutamyl-prolyl-tRNA synthetase. | Tyrosine--tRNA ligase. | 0.985 |