Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
sfxn2Sidoreflexin. (321 aa)    
Predicted Functional Partners:
slc16a5a
Solute carrier family 16 member 5a.
    
 
 0.737
znf1013
Zinc finger protein 1013.
      
 0.719
tia1l
Cytotoxic granule-associated RNA-binding protein 1,-like.
    
 
 0.690
spg7
SPG7 matrix AAA peptidase subunit, paraplegin.
    
   0.619
eif1b
Zgc:56676.
      
 0.613
ndufaf6
NADH:ubiquinone oxidoreductase complex assembly factor 6.
      
 0.596
slc25a19
Solute carrier family 25 member 19; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
  
 0.588
tra2a
Transformer 2 alpha homolog.
      
 0.571
mthfd1b
Methylenetetrahydrofolate dehydrogenase (NADP+-dependent) 1b.
   
 
 0.566
sfxn4
Sideroflexin-4; Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity).
  
 
0.533
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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