Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mtmr1bMyotubularin-related protein 1b. (649 aa)    
Predicted Functional Partners:
pikfyve
Phosphatidylinositol phosphate 5-kinase type III isoform d.
     
 0.905
pik3c3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
     
 0.903
cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
     
 0.887
plcb3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
     
 0.879
Plcb2
Phosphoinositide phospholipase C.
     
 0.879
inpp4b
Inositol polyphosphate-4-phosphatase type II B.
     
 0.877
inpp4aa
Inositol polyphosphate-4-phosphatase type I Aa.
     
 0.877
inpp4ab
Inositol polyphosphate-4-phosphatase type I Ab.
     
 0.877
pip4p1a
Type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase-A; Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate.
     
 0.875
pip4k2aa
Similar to type II phosphatidylinositolphosphate kinase-alpha.
    
  0.874
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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