Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sfr1Swi5-dependent recombination DNA repair protein 1 homolog; Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination. (201 aa)    
Predicted Functional Partners:
swi5
SWI5 homologous recombination repair protein.
   
 0.990
rad51d
DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily.
   
 0.782
meiob
Methionine sulfoxide reductase B1b.
      
 0.746
lsm6
LSM6 homolog, U6 small nuclear RNA and mRNA degradation-associated.
      
 0.727
rad51b
RAD51 paralog B.
   
 0.725
prpf18
Pre-mRNA-splicing factor 18; Participates in the second step of pre-mRNA splicing.
      
 0.701
gcc1
GRIP and coiled-coil domain-containing 1.
      
 0.699
xrcc3
DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.
    
 0.651
rcbtb2
Regulator of chromosome condensation (RCC1) and BTB (POZ) domain-containing protein 2.
      
 0.594
rad51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
    
 
 0.515
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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