Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hbl4Hexose-binding lectin 4. (245 aa)    
Predicted Functional Partners:
lectin
Lectin.
  
   
 0.899
c3a.2
Complement component c3a, duplicate 2.
   
 0.856
c1r
Complement component 1, r subcomponent; Belongs to the peptidase S1 family.
   
 0.840
masp2
Mannan-binding lectin serine peptidase 2; Belongs to the peptidase S1 family.
   
 0.836
serping1
Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; Belongs to the serpin family.
   
 
 0.811
c1s
Complement component 1, s subcomponent.
    
 0.740
F1QJB3_DANRE
Si:ch1073-280e3.1; Belongs to the peptidase S1 family.
   
 0.719
lman2lb
Lectin, mannose-binding 2-like b.
    
 
 0.718
masp1
Mannan-binding lectin serine peptidase 1; Belongs to the peptidase S1 family.
   
 0.717
cfi
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 0.702
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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