Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ppp1r8bProtein phosphatase 1, regulatory subunit 8b. (349 aa)    
Predicted Functional Partners:
ppp1r7
Protein phosphatase 1 regulatory subunit 7; Regulatory subunit of protein phosphatase 1; Belongs to the SDS22 family.
   
 
 0.840
ppp1cb
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 
 0.788
ppp1cbl
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 
 0.788
ppp1r11
E3 ubiquitin-protein ligase PPP1R11; Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Inhibitor of protein phosphatase 1.
    
 
 0.718
ppp1caa
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 
 0.706
ppp1cab
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 
 0.706
ppp1cc
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 
 0.706
suox
Sulfite oxidase.
      
 0.691
ctnnbl1
Catenin, beta-like 1.
   
   0.684
ppp1r2
Protein phosphatase 1, regulatory (inhibitor) subunit 2.
    
 
 0.632
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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