STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spryd4SPRY domain-containing 4. (223 aa)    
Predicted Functional Partners:
GTPBP8
GTP-binding protein 8.
   
  
 0.875
GPR89B
Si:ch73-390b10.2.
    
 
 0.833
yeats4
YEATS domain-containing 4.
      
 0.825
gls2a
Glutaminase 2a (liver, mitochondrial).
   
  
 0.822
ccnt1
Cyclin T1; Belongs to the cyclin family.
    
 
 0.759
tmem192
Transmembrane protein 192; Belongs to the TMEM192 family.
   
   0.687
or126-1
Olfactory receptor.
      
 0.542
cpsf6
Cleavage and polyadenylation specificity factor subunit 6; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
   
  
 0.537
ankrd46b
Ankyrin repeat domain-containing protein 46.
    
 
 0.477
crygm2e
Crystallin, gamma M2e; Belongs to the beta/gamma-crystallin family.
  
     0.453
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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