Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
spryd4SPRY domain-containing 4. (223 aa)    
Predicted Functional Partners:
GTPBP8
GTP-binding protein 8.
   
  
 0.864
GPR89B
Si:ch73-390b10.2.
      
 0.834
gls2a
Glutaminase 2a (liver, mitochondrial).
      
 0.780
tmem192
Transmembrane protein 192; Belongs to the TMEM192 family.
   
   0.779
yeats4
YEATS domain-containing 4.
      
 0.765
ccnt1
Cyclin T1; Belongs to the cyclin family.
    
 
 0.684
ankrd46b
Ankyrin repeat domain-containing protein 46.
    
 
 0.606
sppl2
Signal peptide peptidase-like 2.
      
 0.604
cpped1
Serine/threonine-protein phosphatase CPPED1; Protein phosphatase involved in the dephosphorylation of AKT kinase family.
     
 0.509
cpm
Carboxypeptidase M.
      
 0.506
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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