Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cotl1Coactosin-like F-actin-binding protein 1. (142 aa)    
Predicted Functional Partners:
E9QGC1_DANRE
Si:dkey-17e16.9.
    
 
 0.947
btbd10b
BTB (POZ) domain-containing 10b.
      
 0.737
capzb
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.734
F1QCI4_DANRE
Si:ch211-264f5.2.
    
 
 0.723
gmip
GEM-interacting protein.
   
  
 0.620
cap1
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 
 0.613
cap2
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 
 0.613
alox5ap
Arachidonate 5-lipoxygenase-activating protein.
      
 0.612
cfl1l
Cofilin 1 (non-muscle),-like; Belongs to the actin-binding proteins ADF family.
   
 
 0.599
gpr17
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.598
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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