STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serpinh1bSerpin peptidase inhibitor, clade H (heat shock protein 47), member 1b; Belongs to the serpin family. (405 aa)    
Predicted Functional Partners:
col1a1a
Collagen, type I, alpha 1a.
   
 0.791
col10a1b
Collagen, type X, alpha 1b.
   
 0.703
ctage5
MIA SH3 domain ER export factor 2.
   
  
 0.696
crtap
Cartilage-associated protein.
   
 
 0.692
hsp70.3
Heat shock cognate 70-kd protein, tandem duplicate 3; Belongs to the heat shock protein 70 family.
   
  
 0.684
col2a1a
Collagen, type II, alpha 1a.
   
 0.680
p3h1
Prolyl 3-hydroxylase 1.
   
 
 0.673
col5a3a
Collagen, type V, alpha 3a.
   
 0.643
col4a5
Collagen, type IV, alpha 5 (Alport syndrome).
   
 0.627
p4ha2
Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2.
   
  
 0.626
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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