Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ckmaCreatine kinase, muscle a; Belongs to the ATP:guanido phosphotransferase family. (381 aa)    
Predicted Functional Partners:
ckbb
Brain-subtype creatine kinase; Belongs to the ATP:guanido phosphotransferase family.
  
 
0.986
gamt
Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Important in nervous system development; Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
   
 
 0.966
ckmb
Creatine kinase, muscle b; Belongs to the ATP:guanido phosphotransferase family.
  
 
0.958
ckmt1
Creatine kinase, mitochondrial 1; Belongs to the ATP:guanido phosphotransferase family.
   
  0.897
got2b
Aspartate aminotransferase.
   
 
 0.878
ckba
Creatine kinase, brain a; Belongs to the ATP:guanido phosphotransferase family.
     
  0.871
got2a
Aspartate aminotransferase.
   
 
 0.868
got1
Aspartate aminotransferase.
   
 
 0.862
mb
Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
   
 
 0.848
myog
Myogenin.
   
 
 0.821
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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