Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
kbtbd12Kelch repeat and BTB domain-containing protein 12. (623 aa)    
Predicted Functional Partners:
kcng3
Potassium voltage-gated channel, subfamily G, member 3; Belongs to the potassium channel family.
      
 0.908
rrp36
Ribosomal RNA-processing 36.
   
  
 0.865
ccdc36
Coiled-coil domain-containing 36.
      
 0.861
xpc
Xeroderma pigmentosum, complementation group C.
  
   
 0.812
trappc6b
Trafficking protein particle complex subunit 6b; Component of a transport protein particle (TRAPP) complex that may function in specific stages of inter-organelle traffic. Specifically involved in the early development of neural circuitry, likely by controlling the frequency and amplitude of intracellular calcium transients implicated in the regulation of neuron differentiation and survival.
      
 0.797
tmem204
Transmembrane protein 204.
   
  
 0.774
rab11fip3
Rab11 family-interacting protein 3.
      
 0.753
klc4
Kinesin light chain 4.
    
 0.751
decr2
Peroxisomal 2,4-dienoyl-CoA reductase; Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA (By similarity).
      
 0.748
ift140
Intraflagellar transport 140 homolog (Chlamydomonas).
      
 0.747
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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