Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hsdl2Hydroxysteroid dehydrogenase-like protein 2; Has apparently no steroid dehydrogenase activity. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (415 aa)    
Predicted Functional Partners:
eci2
Enoyl-CoA delta isomerase 2.
  
 0.959
hadh
Hydroxyacyl-Coenzyme A dehydrogenase.
  
 0.921
acox1
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 0.901
adhfe1
Alcohol dehydrogenase iron-containing 1.
  
 0.881
acaa2
Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.869
hadhb
Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.860
amacr
Alpha-methylacyl-CoA racemase.
  
 0.856
sugct
Succinyl-CoA:glutarate-CoA transferase.
  
 0.856
cdyl
Chromodomain protein, Y-like.
  
 0.855
cryl1
Crystallin, lambda 1.
  
 0.852
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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