node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
atoh7 | foxn4 | ENSDARP00000092102 | ENSDARP00000020367 | Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. | Forkhead box protein N4; Transcription factor essential for neural and some non-neural tissues development. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates. Drives commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the [...] | 0.772 |
atoh7 | isl1 | ENSDARP00000092102 | ENSDARP00000012903 | Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. | Insulin gene enhancer protein isl-1; DNA-binding transcriptional activator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. May be involved in subtype specialization of primary motoneurons. May bind to insulin gene enhancer sequences. Essential for heart development (By similarity). | 0.773 |
atoh7 | pou4f1 | ENSDARP00000092102 | ENSDARP00000007850 | Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. | POU domain protein. | 0.681 |
atoh7 | pou4f2 | ENSDARP00000092102 | ENSDARP00000111629 | Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. | POU domain protein. | 0.884 |
atoh7 | six3a | ENSDARP00000092102 | ENSDARP00000075254 | Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. | Sine oculis homeobox homolog 3a. | 0.747 |
atoh7 | six3b | ENSDARP00000092102 | ENSDARP00000071625 | Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. | Sine oculis homeobox homolog 3b. | 0.812 |
atoh7 | vsx2 | ENSDARP00000092102 | ENSDARP00000038309 | Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. | Visual system homeobox 2; Acts as a transcriptional regulator (By similarity). Mediates the differentiation of V2a interneurons (By similarity). Plays a role in eye development and organization of the neuroretina. | 0.905 |
calb1 | isl1 | ENSDARP00000115794 | ENSDARP00000012903 | Calbindin 1. | Insulin gene enhancer protein isl-1; DNA-binding transcriptional activator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. May be involved in subtype specialization of primary motoneurons. May bind to insulin gene enhancer sequences. Essential for heart development (By similarity). | 0.531 |
calb1 | pou4f1 | ENSDARP00000115794 | ENSDARP00000007850 | Calbindin 1. | POU domain protein. | 0.721 |
calb1 | pou4f2 | ENSDARP00000115794 | ENSDARP00000111629 | Calbindin 1. | POU domain protein. | 0.673 |
calb1 | rcvrn2 | ENSDARP00000115794 | ENSDARP00000011506 | Calbindin 1. | Recoverin-2a. | 0.727 |
calb1 | rcvrnb | ENSDARP00000115794 | ENSDARP00000144981 | Calbindin 1. | Recoverin-1b. | 0.745 |
calb1 | vsx2 | ENSDARP00000115794 | ENSDARP00000038309 | Calbindin 1. | Visual system homeobox 2; Acts as a transcriptional regulator (By similarity). Mediates the differentiation of V2a interneurons (By similarity). Plays a role in eye development and organization of the neuroretina. | 0.811 |
foxn4 | atoh7 | ENSDARP00000020367 | ENSDARP00000092102 | Forkhead box protein N4; Transcription factor essential for neural and some non-neural tissues development. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates. Drives commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the [...] | Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. | 0.772 |
foxn4 | isl1 | ENSDARP00000020367 | ENSDARP00000012903 | Forkhead box protein N4; Transcription factor essential for neural and some non-neural tissues development. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates. Drives commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the [...] | Insulin gene enhancer protein isl-1; DNA-binding transcriptional activator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. May be involved in subtype specialization of primary motoneurons. May bind to insulin gene enhancer sequences. Essential for heart development (By similarity). | 0.622 |
foxn4 | pou4f2 | ENSDARP00000020367 | ENSDARP00000111629 | Forkhead box protein N4; Transcription factor essential for neural and some non-neural tissues development. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates. Drives commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the [...] | POU domain protein. | 0.725 |
foxn4 | six3b | ENSDARP00000020367 | ENSDARP00000071625 | Forkhead box protein N4; Transcription factor essential for neural and some non-neural tissues development. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates. Drives commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the [...] | Sine oculis homeobox homolog 3b. | 0.430 |
foxn4 | vsx2 | ENSDARP00000020367 | ENSDARP00000038309 | Forkhead box protein N4; Transcription factor essential for neural and some non-neural tissues development. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates. Drives commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the [...] | Visual system homeobox 2; Acts as a transcriptional regulator (By similarity). Mediates the differentiation of V2a interneurons (By similarity). Plays a role in eye development and organization of the neuroretina. | 0.834 |
isl1 | atoh7 | ENSDARP00000012903 | ENSDARP00000092102 | Insulin gene enhancer protein isl-1; DNA-binding transcriptional activator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. May be involved in subtype specialization of primary motoneurons. May bind to insulin gene enhancer sequences. Essential for heart development (By similarity). | Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. | 0.773 |
isl1 | calb1 | ENSDARP00000012903 | ENSDARP00000115794 | Insulin gene enhancer protein isl-1; DNA-binding transcriptional activator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. May be involved in subtype specialization of primary motoneurons. May bind to insulin gene enhancer sequences. Essential for heart development (By similarity). | Calbindin 1. | 0.531 |