Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
oser1Oxidative stress-responsive serine-rich 1. (300 aa)    
Predicted Functional Partners:
krt94
Keratin 94; Belongs to the intermediate filament family.
      
 0.686
serpinh1b
Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b; Belongs to the serpin family.
      
 0.672
zgc:171592
Zgc:171592; Belongs to the peptidase S1 family.
      
 0.664
afp4
Type IV antifreeze protein A.
      
 0.661
LOC568656
Antifreeze protein type IV.
      
 0.629
cldn23a
Claudin 23a.
      
 0.619
E7EY35_DANRE
Si:dkey-238d18.3; Belongs to the peptidase S1 family.
      
 0.597
romo1
Reactive oxygen species modulator 1; Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage (By similarity).
      
 0.594
cirbpa
Cold-inducible RNA-binding protein a.
   
  
 0.570
hsp90aa1.2
Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.
      
 0.538
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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