STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
slc37a2Glucose-6-phosphate exchanger SLC37A2; Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. (494 aa)    
Predicted Functional Partners:
slc17a9b
Solute carrier family 17, member 9b.
  
  
 0.888
tnfrsfa
Tumor necrosis factor receptor superfamily, member a.
   
  
 0.747
ppp1r27a
ANK_REP_REGION domain-containing protein.
   
  
 0.612
hspa4b
Heat shock protein 4b.
   
  
 0.606
rpl36a
60S ribosomal protein L36a.
    
 
 0.597
greb1
Growth-regulating estrogen receptor-binding 1.
   
  
 0.567
fbp2
Fructose-1,6-bisphosphatase 2; Belongs to the FBPase class 1 family.
   
 
 0.499
nfkb2
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100).
   
  
 0.476
gdf6a
Growth/differentiation factor 6-A; Growth factor that controls proliferation and cellular differentiation in the retina. Plays a key role in regulating apoptosis during retinal development. Establishes dorsal-ventral positional information in the retina and controls the formation of the retinotectal map. Functions maternally in dorsal/ventral patterning to induce the expression of the zygotic bmp2b and bmp4 genes and ventralize embryos. Zygotic expression does not appear to regulate axis specification, but instead functions to establish the integrity of the axial vessels during embryon [...]
      
 0.452
heyl
Hairy/enhancer-of-split related with YRPW motif-like protein; Transcriptional repressor which functions as a downstream effector of Notch signaling.
      
 0.452
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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