Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
snrnp40Small nuclear ribonucleoprotein 40 (U5). (347 aa)    
Predicted Functional Partners:
prpf8
Pre-mRNA-processing factor 8.
   
 0.999
prpf6
PRP6 pre-mRNA-processing factor 6 homolog (S. cerevisiae).
   
 0.998
ddx23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.
   
 0.997
snrnp200
Small nuclear ribonucleoprotein 200 (U5).
   
 0.997
txnl4a
Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family.
   
 0.994
eftud2
Elongation factor Tu GTP-binding domain-containing 2.
   
 
 0.993
snrpe
Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
   
 0.993
tssc4
Protein TSSC4; Belongs to the TSSC4 family.
    
 0.984
cd2bp2
CD2 (cytoplasmic tail)-binding protein 2.
   
 0.983
prpf3
PRP3 pre-mRNA-processing factor 3 homolog (yeast).
    
 
 0.978
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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