Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ptgr1Prostaglandin reductase 1. (329 aa)    
Predicted Functional Partners:
lta4h
Leukotriene A(4) hydrolase; Belongs to the peptidase M1 family.
   
 
 0.948
hpgd
15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.927
zgc:56585
Zgc:56585; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.903
ptgr2
Prostaglandin reductase 2.
  
  
0.895
cyp4t8
Cytochrome P450, family 4, subfamily T, polypeptide 8.
   
 
 0.695
LOC108183462
Si:ch211-106j21.6.
      
 0.682
LOC103910514
Si:ch211-76m11.3.
      
 0.682
ENSDARP00000141691
Si:ch211-76m11.3.
      
 0.682
rnh1
Si:ch211-213a13.2.
      
 0.681
F1R805_DANRE
Si:ch211-213a13.2.
      
 0.681
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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