Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
p2rx8P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (391 aa)    
Predicted Functional Partners:
nptx2b
Neuronal pentraxin IIb.
      
 0.930
p2rx2
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
  
0.862
p2rx3b
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
  
 
0.855
entpd3
Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family.
      
 0.836
p2rx4b
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
  
0.798
p2rx7
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.
   
  0.780
grin3a
Glutamate receptor, ionotropic, N-methyl-D-aspartate 3A.
     
  0.740
p2rx1
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
  
  
 
0.735
grin1b
Glutamate receptor, ionotropic, N-methyl D-aspartate 1b.
     
 0.630
grin1a
Glutamate receptor, ionotropic, N-methyl D-aspartate 1a.
     
 0.630
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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