Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pigkGPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (389 aa)    
Predicted Functional Partners:
pigu
Phosphatidylinositol glycan anchor biosynthesis, class U.
    
 0.999
gpaa1
Glycosylphosphatidylinositol anchor attachment 1.
    
 0.999
pigt
Phosphatidylinositol glycan anchor biosynthesis, class T.
   
 0.999
pigs
Phosphatidylinositol glycan anchor biosynthesis, class S.
   
 0.999
PIGG
Si:ch73-49o8.1.
    
 0.997
pgap1
GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi.
    
 0.992
pigf
Phosphatidylinositol glycan anchor biosynthesis, class F.
   
 
 0.979
pigl
Phosphatidylinositol glycan anchor biosynthesis, class L.
      
 0.929
pigo
Phosphatidylinositol glycan anchor biosynthesis, class O.
    
 0.926
pigm
GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly (By similarity).
      
 0.924
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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