close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
itgb1aIntegrin beta; Belongs to the integrin beta chain family. (798 aa)    
Predicted Functional Partners:
ilk
Integrin-linked kinase.
    
 0.993
itga5
Integrin, alpha 5 (fibronectin receptor, alpha polypeptide); Belongs to the integrin alpha chain family.
   
 0.991
itga6a
Integrin, alpha 6a; Belongs to the integrin alpha chain family.
   
 0.986
ptk2ab
Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.979
itga6b
Integrin, alpha 6b; Belongs to the integrin alpha chain family.
   
 0.973
itga6l
Integrin, alpha 6,-like; Belongs to the integrin alpha chain family.
   
 0.973
tln1
Talin 1.
   
 0.973
itga8
Integrin, alpha 8; Belongs to the integrin alpha chain family.
   
 0.972
itgav
Integrin, alpha V; Belongs to the integrin alpha chain family.
   
 0.967
itga4
Integrin alpha 4; Belongs to the integrin alpha chain family.
   
 0.965
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.