Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
itgb1aIntegrin beta; Belongs to the integrin beta chain family. (798 aa)    
Predicted Functional Partners:
tln1
Talin 1.
   
 0.986
ilk
Integrin-linked kinase.
    
 0.982
itga5
Integrin, alpha 5 (fibronectin receptor, alpha polypeptide); Belongs to the integrin alpha chain family.
   
 0.980
itga4
Integrin alpha 4; Belongs to the integrin alpha chain family.
    
 0.960
itga6l
Integrin, alpha 6,-like; Belongs to the integrin alpha chain family.
   
 0.959
itga9
Integrin, alpha 9; Belongs to the integrin alpha chain family.
   
 0.957
ptk2ab
Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.955
itgav
Integrin, alpha V; Belongs to the integrin alpha chain family.
   
 0.954
tln2a
Talin 2a.
   
 0.952
tln2b
Talin 2b.
   
 0.952
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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