Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fam49baFamily with sequence similarity 49 member Ba. (325 aa)    
Predicted Functional Partners:
rac2
Rac family small GTPase 2.
   
 0.960
ankha
ANKH inorganic pyrophosphate transport regulator a.
      
 0.813
lrrc40
Leucine-rich repeat-containing protein 40.
      
 0.771
tex2
Testis-expressed 2.
      
 0.686
klhl7
Kelch-like family member 7.
      
 0.676
arhgef2
Rho/rac guanine nucleotide exchange factor (GEF) 2.
      
 0.616
NFX1
Si:dkey-10f23.2.
      
 0.609
akirin2
Akirin 2.
      
 0.598
lyn
Tyrosine-protein kinase.
      
 0.596
stk17al
Serine/threonine kinase 17a-like.
      
 0.558
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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