Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC558202Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (652 aa)    
Predicted Functional Partners:
tmed10
Transmembrane emp24-like trafficking protein 10 (Yeast).
   
  
 0.789
tm9sf3
Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
  
  
0.724
golim4a-2
Golgi integral membrane protein 4a.
      
 0.697
galnt2
Polypeptide N-acetylgalactosaminyltransferase.
      
 0.617
vps54
VPS54 subunit of GARP complex.
      
 0.550
sptlc1
Serine palmitoyltransferase, long chain base subunit 1.
   
  
 0.504
sptssa
Serine palmitoyltransferase small subunit A; Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference (By similarity). Belongs to the SPTSS family. SPTSSA subfamily.
      
 0.494
hvcn1
Voltage-gated hydrogen channel 1; Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient (By similarity).
      
 0.447
sys1
Protein SYS1 homolog; Involved in protein trafficking. Belongs to the SYS1 family.
      
 0.447
mettl13
eEF1A lysine and N-terminal methyltransferase; Dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (eef1a1 and eef1a2) at two different positions, and is therefore involved in the regulation of mRNA translation. Via its C-terminus, methylates the N-terminus of eef1a1 and eef1a2. Via its N-terminus dimethylates lysine residues of eef1a1 and eef1a2.
      
 0.442
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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