btbd6b protein (Danio rerio) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
btbd6b	cul3a	ENSDARP00000039906	ENSDARP00000056881	BTB/POZ domain-containing protein 6-B; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex. Promotes the export of zbtb16/plzf from the nucleus to the cytoplasm and targets zbtb16/plzf for ubiquitination and degradation. Up-regulates neurog1 expression and antagonizes zbtb16/plzf, to promote neurogenesis (By similarity).	Cullin 3a; Belongs to the cullin family.	0.656
btbd6b	cul3b	ENSDARP00000039906	ENSDARP00000132246	BTB/POZ domain-containing protein 6-B; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex. Promotes the export of zbtb16/plzf from the nucleus to the cytoplasm and targets zbtb16/plzf for ubiquitination and degradation. Up-regulates neurog1 expression and antagonizes zbtb16/plzf, to promote neurogenesis (By similarity).	Cullin 3b; Belongs to the cullin family.	0.784
btbd6b	kctd6b	ENSDARP00000039906	ENSDARP00000034172	BTB/POZ domain-containing protein 6-B; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex. Promotes the export of zbtb16/plzf from the nucleus to the cytoplasm and targets zbtb16/plzf for ubiquitination and degradation. Up-regulates neurog1 expression and antagonizes zbtb16/plzf, to promote neurogenesis (By similarity).	BTB/POZ domain-containing protein KCTD6; Probable substrate-specific adapter of a cullin-containing E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins.	0.729
btbd6b	myt1la	ENSDARP00000039906	ENSDARP00000127218	BTB/POZ domain-containing protein 6-B; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex. Promotes the export of zbtb16/plzf from the nucleus to the cytoplasm and targets zbtb16/plzf for ubiquitination and degradation. Up-regulates neurog1 expression and antagonizes zbtb16/plzf, to promote neurogenesis (By similarity).	Myelin transcription factor 1-like, a.	0.600
btbd6b	nudt22	ENSDARP00000039906	ENSDARP00000121110	BTB/POZ domain-containing protein 6-B; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex. Promotes the export of zbtb16/plzf from the nucleus to the cytoplasm and targets zbtb16/plzf for ubiquitination and degradation. Up-regulates neurog1 expression and antagonizes zbtb16/plzf, to promote neurogenesis (By similarity).	Nudix (nucleoside diphosphate-linked moiety X)-type motif 22.	0.618
btbd6b	tbr1a	ENSDARP00000039906	ENSDARP00000040179	BTB/POZ domain-containing protein 6-B; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex. Promotes the export of zbtb16/plzf from the nucleus to the cytoplasm and targets zbtb16/plzf for ubiquitination and degradation. Up-regulates neurog1 expression and antagonizes zbtb16/plzf, to promote neurogenesis (By similarity).	T-box brain transcription factor 1a.	0.662
btbd6b	tnrc18	ENSDARP00000039906	ENSDARP00000129614	BTB/POZ domain-containing protein 6-B; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex. Promotes the export of zbtb16/plzf from the nucleus to the cytoplasm and targets zbtb16/plzf for ubiquitination and degradation. Up-regulates neurog1 expression and antagonizes zbtb16/plzf, to promote neurogenesis (By similarity).	Trinucleotide repeat-containing 18.	0.740
btbd6b	zbtb44	ENSDARP00000039906	ENSDARP00000128160	BTB/POZ domain-containing protein 6-B; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex. Promotes the export of zbtb16/plzf from the nucleus to the cytoplasm and targets zbtb16/plzf for ubiquitination and degradation. Up-regulates neurog1 expression and antagonizes zbtb16/plzf, to promote neurogenesis (By similarity).	Zinc finger and BTB domain-containing 44.	0.669
btbd6b	zbtb7c	ENSDARP00000039906	ENSDARP00000137843	BTB/POZ domain-containing protein 6-B; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex. Promotes the export of zbtb16/plzf from the nucleus to the cytoplasm and targets zbtb16/plzf for ubiquitination and degradation. Up-regulates neurog1 expression and antagonizes zbtb16/plzf, to promote neurogenesis (By similarity).	Zinc finger and BTB domain-containing 7C.	0.594
btbd6b	znf296	ENSDARP00000039906	ENSDARP00000089751	BTB/POZ domain-containing protein 6-B; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex. Promotes the export of zbtb16/plzf from the nucleus to the cytoplasm and targets zbtb16/plzf for ubiquitination and degradation. Up-regulates neurog1 expression and antagonizes zbtb16/plzf, to promote neurogenesis (By similarity).	Zinc finger protein 296.	0.663
cul3a	btbd6b	ENSDARP00000056881	ENSDARP00000039906	Cullin 3a; Belongs to the cullin family.	BTB/POZ domain-containing protein 6-B; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex. Promotes the export of zbtb16/plzf from the nucleus to the cytoplasm and targets zbtb16/plzf for ubiquitination and degradation. Up-regulates neurog1 expression and antagonizes zbtb16/plzf, to promote neurogenesis (By similarity).	0.656
cul3a	kctd6b	ENSDARP00000056881	ENSDARP00000034172	Cullin 3a; Belongs to the cullin family.	BTB/POZ domain-containing protein KCTD6; Probable substrate-specific adapter of a cullin-containing E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins.	0.967
cul3b	btbd6b	ENSDARP00000132246	ENSDARP00000039906	Cullin 3b; Belongs to the cullin family.	BTB/POZ domain-containing protein 6-B; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex. Promotes the export of zbtb16/plzf from the nucleus to the cytoplasm and targets zbtb16/plzf for ubiquitination and degradation. Up-regulates neurog1 expression and antagonizes zbtb16/plzf, to promote neurogenesis (By similarity).	0.784
cul3b	kctd6b	ENSDARP00000132246	ENSDARP00000034172	Cullin 3b; Belongs to the cullin family.	BTB/POZ domain-containing protein KCTD6; Probable substrate-specific adapter of a cullin-containing E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins.	0.979
kctd6b	btbd6b	ENSDARP00000034172	ENSDARP00000039906	BTB/POZ domain-containing protein KCTD6; Probable substrate-specific adapter of a cullin-containing E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins.	BTB/POZ domain-containing protein 6-B; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex. Promotes the export of zbtb16/plzf from the nucleus to the cytoplasm and targets zbtb16/plzf for ubiquitination and degradation. Up-regulates neurog1 expression and antagonizes zbtb16/plzf, to promote neurogenesis (By similarity).	0.729
kctd6b	cul3a	ENSDARP00000034172	ENSDARP00000056881	BTB/POZ domain-containing protein KCTD6; Probable substrate-specific adapter of a cullin-containing E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins.	Cullin 3a; Belongs to the cullin family.	0.967
kctd6b	cul3b	ENSDARP00000034172	ENSDARP00000132246	BTB/POZ domain-containing protein KCTD6; Probable substrate-specific adapter of a cullin-containing E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins.	Cullin 3b; Belongs to the cullin family.	0.979
kctd6b	zbtb44	ENSDARP00000034172	ENSDARP00000128160	BTB/POZ domain-containing protein KCTD6; Probable substrate-specific adapter of a cullin-containing E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins.	Zinc finger and BTB domain-containing 44.	0.594
kctd6b	zbtb7c	ENSDARP00000034172	ENSDARP00000137843	BTB/POZ domain-containing protein KCTD6; Probable substrate-specific adapter of a cullin-containing E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins.	Zinc finger and BTB domain-containing 7C.	0.561
myt1la	btbd6b	ENSDARP00000127218	ENSDARP00000039906	Myelin transcription factor 1-like, a.	BTB/POZ domain-containing protein 6-B; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex. Promotes the export of zbtb16/plzf from the nucleus to the cytoplasm and targets zbtb16/plzf for ubiquitination and degradation. Up-regulates neurog1 expression and antagonizes zbtb16/plzf, to promote neurogenesis (By similarity).	0.600

page 1 of 2

Server load: low (18%) [HD]

Share

Network

Co-occurrence

Experiments

Co-expression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About