Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
myl7Myosin, light polypeptide 7, regulatory. (172 aa)    
Predicted Functional Partners:
myh6
Myosin, heavy chain 6, cardiac muscle, alpha; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.979
actb2
Actin, cytoplasmic 2, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.
    
 0.978
myh7
Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.968
rock2a
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
    
 0.964
myh10
Myosin, heavy chain 10, non-muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.959
rock1
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
    
 0.957
ppp1r12c
Protein phosphatase 1, regulatory subunit 12C.
    
 0.955
ENSDARP00000154801
PRKG1_interact domain-containing protein.
    
 0.955
mylka
Myosin, light chain kinase a.
    
 0.953
mylk5
Myosin, light chain kinase 5.
    
 0.949
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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