STRINGSTRING
tnrc5 protein (Danio rerio) - STRING interaction network
"tnrc5" - Trinucleotide repeat containing 5 in Danio rerio
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tnrc5Trinucleotide repeat containing 5; Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for immune responses (By similarity) (276 aa)    
Predicted Functional Partners:
lrrc40
Leucine rich repeat containing 40 (601 aa)
     
      0.631
ogn
Osteoglycin (292 aa)
       
      0.527
zgc:193598
Osteoglycin (245 aa)
       
      0.527
ZC3H8
Zinc finger CCCH-type containing 8 (1070 aa)
           
  0.507
polr1b
Polymerase (RNA) I polypeptide B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1132 aa)
           
  0.476
znhit1
Zinc finger, HIT-type containing 1 (154 aa)
     
   
  0.461
gnmt
Glycine N-methyltransferase (294 aa)
           
  0.461
gltscr1l
Uncharacterized protein (753 aa)
     
   
  0.457
eif4a3
Eukaryotic translation initiation factor 4A, isoform 3; ATP-dependent RNA helicase. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRN [...] (406 aa)
     
   
  0.457
zgc:110314
Kinesin light chain 4 (631 aa)
           
  0.454
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio, Brachydanio rerio, Brachydanio rerio frankei, Celestichthys, Cyprinidae, Cypriniformes, Cypriniphysi, Cyprinoidea, Cyprinoidei, Cyprinus rerio, D. rerio, Danio, Danio frankei, Danio rerio, Danio rerio frankei, Ostariophysi, Otocephala, Otophysi, leopard danio, zebra danio, zebra fish, zebrafish
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