Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
tbr1aT-box brain transcription factor 1a. (585 aa)    
Predicted Functional Partners:
tnrc18
Trinucleotide repeat-containing 18.
    
 
 0.791
myt1la
Myelin transcription factor 1-like, a.
   
  
 0.741
znf296
Zinc finger protein 296.
    
 
 0.739
btbd6b
BTB/POZ domain-containing protein 6-B; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex. Promotes the export of zbtb16/plzf from the nucleus to the cytoplasm and targets zbtb16/plzf for ubiquitination and degradation. Up-regulates neurog1 expression and antagonizes zbtb16/plzf, to promote neurogenesis (By similarity).
    
 
 0.662
egr3
Early growth response 3.
    
 
 0.642
klhl41a
Kelch-like protein 41a; Involved in skeletal muscle development and differentiation.
    
 
 0.598
PITPNC1
Phosphatidylinositol transfer protein cytoplasmic 1.
      
 0.594
neurod6b
Neurogenic differentiation factor 6-B; Differentiation factor required for neurogenesis (By similarity). Does not act as an upstream activator of isl1.
   
 
 0.578
vent
Ventral-expressed homeobox.
    
 
 0.574
aff2
AF4/FMR2 family, member 2.
    
 
 0.567
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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