STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbr1aT-box brain transcription factor 1a. (585 aa)    
Predicted Functional Partners:
znf296
Zinc finger protein 296.
    
 
 0.828
myt1la
Myelin transcription factor 1-like, a.
   
  
 0.751
tnrc18
Trinucleotide repeat-containing 18.
    
 
 0.746
klhl41a
Kelch-like protein 41a; Involved in skeletal muscle development and differentiation.
   
  
 0.656
btbd6b
BTB/POZ domain-containing protein 6-B; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex. Promotes the export of zbtb16/plzf from the nucleus to the cytoplasm and targets zbtb16/plzf for ubiquitination and degradation. Up-regulates neurog1 expression and antagonizes zbtb16/plzf, to promote neurogenesis (By similarity).
   
  
 0.651
egr3
Early growth response 3.
   
 
 0.621
PITPNC1
Phosphatidylinositol transfer protein cytoplasmic 1.
   
  
 0.607
neurod6b
Neurogenic differentiation factor 6-B; Differentiation factor required for neurogenesis (By similarity). Does not act as an upstream activator of isl1.
   
  
 0.607
nfil3-6
Nuclear factor, interleukin 3-regulated, member 6.
    
 
 0.579
aff2
AF4/FMR2 family, member 2.
    
 
 0.570
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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