Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
tenm1Teneurin transmembrane protein 1. (2736 aa)    
Predicted Functional Partners:
aff2
AF4/FMR2 family, member 2.
   
  
 0.804
nrxn2b
Neurexin 2b beta.
   
  
 0.785
LOC796210
Discs, large (Drosophila) homolog-associated protein 2b.
      
 0.739
ANOS1
Uncharacterized protein.
      
 0.728
A5WWI9_DANRE
Si:ch73-92i20.1.
      
 0.619
mtnr1c
Melatonin receptor type 1C; High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity (By similarity); Belongs to the G-protein coupled receptor 1 family.
      
 0.617
txndc5
Thioredoxin domain-containing 5; Belongs to the protein disulfide isomerase family.
   
  
 0.615
trim71
E3 ubiquitin-protein ligase TRIM71; E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance. Binds to miRNAs and participates in post-transcriptional repression of transcripts. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development.
      
 0.611
LTN1
Si:dkey-175g6.5.
      
 0.600
nav3
Neuron navigator 3; May be involved in neuron regeneration; Belongs to the Nav/unc-53 family.
    
 
 0.596
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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