| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ASS1 | adsl | ENSDARP00000140635 | ENSDARP00000022310 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.542 |
| ASS1 | arg1 | ENSDARP00000140635 | ENSDARP00000097045 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | Arginase. | 0.753 |
| ASS1 | arg2 | ENSDARP00000140635 | ENSDARP00000057376 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | Arginase. | 0.735 |
| ASS1 | asl | ENSDARP00000140635 | ENSDARP00000040189 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | Argininosuccinate lyase. | 0.999 |
| ASS1 | nags | ENSDARP00000140635 | ENSDARP00000101563 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | N-acetylglutamate synthase, conserved domain form; Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (cps1) activity. Belongs to the acetyltransferase family. | 0.998 |
| ASS1 | nos1 | ENSDARP00000140635 | ENSDARP00000135654 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | Nitric oxide synthase; Produces nitric oxide (NO). | 0.587 |
| ASS1 | nos2a | ENSDARP00000140635 | ENSDARP00000106851 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | Nitric oxide synthase; Produces nitric oxide (NO). | 0.518 |
| ASS1 | nos2b | ENSDARP00000140635 | ENSDARP00000048846 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | Nitric oxide synthase; Produces nitric oxide (NO). | 0.516 |
| ASS1 | oat | ENSDARP00000140635 | ENSDARP00000125055 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.989 |
| ASS1 | otc | ENSDARP00000140635 | ENSDARP00000083959 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.997 |
| adsl | ASS1 | ENSDARP00000022310 | ENSDARP00000140635 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | 0.542 |
| adsl | arg1 | ENSDARP00000022310 | ENSDARP00000097045 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Arginase. | 0.479 |
| adsl | arg2 | ENSDARP00000022310 | ENSDARP00000057376 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Arginase. | 0.479 |
| adsl | asl | ENSDARP00000022310 | ENSDARP00000040189 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Argininosuccinate lyase. | 0.949 |
| adsl | nags | ENSDARP00000022310 | ENSDARP00000101563 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | N-acetylglutamate synthase, conserved domain form; Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (cps1) activity. Belongs to the acetyltransferase family. | 0.638 |
| arg1 | ASS1 | ENSDARP00000097045 | ENSDARP00000140635 | Arginase. | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | 0.753 |
| arg1 | adsl | ENSDARP00000097045 | ENSDARP00000022310 | Arginase. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.479 |
| arg1 | arg2 | ENSDARP00000097045 | ENSDARP00000057376 | Arginase. | Arginase. | 0.906 |
| arg1 | asl | ENSDARP00000097045 | ENSDARP00000040189 | Arginase. | Argininosuccinate lyase. | 0.993 |
| arg1 | nags | ENSDARP00000097045 | ENSDARP00000101563 | Arginase. | N-acetylglutamate synthase, conserved domain form; Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (cps1) activity. Belongs to the acetyltransferase family. | 0.821 |