Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
snd1Staphylococcal nuclease domain-containing protein 1. (913 aa)    
Predicted Functional Partners:
lrrc59
Leucine-rich repeat-containing protein 59; Required for nuclear import of FGF1.
   
 
 0.954
rps9
Ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family.
    
 
 0.952
rps2
Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.
   
 
 0.949
mtdhb
Metadherin b.
    
 
 0.836
mtdha
Metadherin a.
    
 
 0.836
rps3
Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
   
 
 0.808
rbm28
RNA-binding motif protein 28.
   
  
 0.794
nudcd1
NudC domain-containing protein 1.
    
   0.790
dicer1
Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, al [...]
   
 
 0.757
drosha
Drosha ribonuclease III.
   
  
 0.748
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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