| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ap5b1 | kbtbd2 | ENSDARP00000128763 | ENSDARP00000110552 | Adaptor-related protein complex 5 subunit beta 1. | Kelch repeat and BTB (POZ) domain-containing 2. | 0.876 |
| ap5b1 | tspan9a | ENSDARP00000128763 | ENSDARP00000040499 | Adaptor-related protein complex 5 subunit beta 1. | Tetraspanin. | 0.777 |
| capza1b | cttnbp2nlb | ENSDARP00000072971 | ENSDARP00000123484 | F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. | CTTNBP2 N-terminal-like b. | 0.799 |
| capza1b | ppfibp1a | ENSDARP00000072971 | ENSDARP00000131924 | F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. | PPFIA-binding protein 1a. | 0.894 |
| capza1b | tigara | ENSDARP00000072971 | ENSDARP00000097862 | F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. | Probable fructose-2,6-bisphosphatase TIGAR A; Fructose-bisphosphatase hydrolyzing fructose-2,6-bisphosphate as well as fructose-1,6-bisphosphate. Acts as a negative regulator of glycolysis by lowering intracellular levels of fructose-2,6- bisphosphate in a p53/TP53-dependent manner, resulting in the pentose phosphate pathway (PPP) activation and NADPH production. Contributes to the generation of reduced glutathione to cause a decrease in intracellular reactive oxygen species (ROS) content, correlating with its ability to protect cells from oxidative or metabolic stress-induced cell dea [...] | 0.815 |
| capza1b | tigarb | ENSDARP00000072971 | ENSDARP00000067391 | F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. | Fructose-2,6-bisphosphatase TIGAR B; Fructose-bisphosphatase hydrolyzing fructose-2,6-bisphosphate as well as fructose-1,6-bisphosphate. Acts as a negative regulator of glycolysis by lowering intracellular levels of fructose-2,6- bisphosphate in a p53/TP53-dependent manner, resulting in the pentose phosphate pathway (PPP) activation and NADPH production. Contributes to the generation of reduced glutathione to cause a decrease in intracellular reactive oxygen species (ROS) content, correlating with its ability to protect cells from oxidative or metabolic stress-induced cell death. May p [...] | 0.756 |
| capza1b | tspan9a | ENSDARP00000072971 | ENSDARP00000040499 | F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. | Tetraspanin. | 0.720 |
| cttnbp2nlb | capza1b | ENSDARP00000123484 | ENSDARP00000072971 | CTTNBP2 N-terminal-like b. | F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. | 0.799 |
| cttnbp2nlb | ppfibp1a | ENSDARP00000123484 | ENSDARP00000131924 | CTTNBP2 N-terminal-like b. | PPFIA-binding protein 1a. | 0.815 |
| cttnbp2nlb | tigara | ENSDARP00000123484 | ENSDARP00000097862 | CTTNBP2 N-terminal-like b. | Probable fructose-2,6-bisphosphatase TIGAR A; Fructose-bisphosphatase hydrolyzing fructose-2,6-bisphosphate as well as fructose-1,6-bisphosphate. Acts as a negative regulator of glycolysis by lowering intracellular levels of fructose-2,6- bisphosphate in a p53/TP53-dependent manner, resulting in the pentose phosphate pathway (PPP) activation and NADPH production. Contributes to the generation of reduced glutathione to cause a decrease in intracellular reactive oxygen species (ROS) content, correlating with its ability to protect cells from oxidative or metabolic stress-induced cell dea [...] | 0.720 |
| cttnbp2nlb | tigarb | ENSDARP00000123484 | ENSDARP00000067391 | CTTNBP2 N-terminal-like b. | Fructose-2,6-bisphosphatase TIGAR B; Fructose-bisphosphatase hydrolyzing fructose-2,6-bisphosphate as well as fructose-1,6-bisphosphate. Acts as a negative regulator of glycolysis by lowering intracellular levels of fructose-2,6- bisphosphate in a p53/TP53-dependent manner, resulting in the pentose phosphate pathway (PPP) activation and NADPH production. Contributes to the generation of reduced glutathione to cause a decrease in intracellular reactive oxygen species (ROS) content, correlating with its ability to protect cells from oxidative or metabolic stress-induced cell death. May p [...] | 0.597 |
| cttnbp2nlb | tspan9a | ENSDARP00000123484 | ENSDARP00000040499 | CTTNBP2 N-terminal-like b. | Tetraspanin. | 0.584 |
| kbtbd2 | ap5b1 | ENSDARP00000110552 | ENSDARP00000128763 | Kelch repeat and BTB (POZ) domain-containing 2. | Adaptor-related protein complex 5 subunit beta 1. | 0.876 |
| kbtbd2 | tspan9a | ENSDARP00000110552 | ENSDARP00000040499 | Kelch repeat and BTB (POZ) domain-containing 2. | Tetraspanin. | 0.662 |
| myo19 | tspan9a | ENSDARP00000132809 | ENSDARP00000040499 | Myosin XIX; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | Tetraspanin. | 0.603 |
| nrip2 | tspan9a | ENSDARP00000100294 | ENSDARP00000040499 | Nuclear receptor-interacting protein 2. | Tetraspanin. | 0.739 |
| ppfibp1a | capza1b | ENSDARP00000131924 | ENSDARP00000072971 | PPFIA-binding protein 1a. | F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. | 0.894 |
| ppfibp1a | cttnbp2nlb | ENSDARP00000131924 | ENSDARP00000123484 | PPFIA-binding protein 1a. | CTTNBP2 N-terminal-like b. | 0.815 |
| ppfibp1a | tigara | ENSDARP00000131924 | ENSDARP00000097862 | PPFIA-binding protein 1a. | Probable fructose-2,6-bisphosphatase TIGAR A; Fructose-bisphosphatase hydrolyzing fructose-2,6-bisphosphate as well as fructose-1,6-bisphosphate. Acts as a negative regulator of glycolysis by lowering intracellular levels of fructose-2,6- bisphosphate in a p53/TP53-dependent manner, resulting in the pentose phosphate pathway (PPP) activation and NADPH production. Contributes to the generation of reduced glutathione to cause a decrease in intracellular reactive oxygen species (ROS) content, correlating with its ability to protect cells from oxidative or metabolic stress-induced cell dea [...] | 0.878 |
| ppfibp1a | tigarb | ENSDARP00000131924 | ENSDARP00000067391 | PPFIA-binding protein 1a. | Fructose-2,6-bisphosphatase TIGAR B; Fructose-bisphosphatase hydrolyzing fructose-2,6-bisphosphate as well as fructose-1,6-bisphosphate. Acts as a negative regulator of glycolysis by lowering intracellular levels of fructose-2,6- bisphosphate in a p53/TP53-dependent manner, resulting in the pentose phosphate pathway (PPP) activation and NADPH production. Contributes to the generation of reduced glutathione to cause a decrease in intracellular reactive oxygen species (ROS) content, correlating with its ability to protect cells from oxidative or metabolic stress-induced cell death. May p [...] | 0.799 |
