Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
add3aAdducin 3 (gamma) a. (672 aa)    
Predicted Functional Partners:
xpnpep1
X-prolyl aminopeptidase (Aminopeptidase P) 1, Soluble; Belongs to the peptidase M24B family.
  
  
 0.929
gpc1a
Secreted glypican-1; Cell surface proteoglycan that bears heparan sulfate; Belongs to the glypican family.
    
 
 0.818
gpc1b
Glypican 1b; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
 
 0.818
xylb
Xylulokinase homolog (H. influenzae).
  
 
 0.768
mri1
Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
  
 
 0.752
adi1
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family.
  
 
 0.745
EFEMP1
EGF containing fibulin extracellular matrix protein 1.
    
 0.743
sptan1
Spectrin alpha, non-erythrocytic 1.
   
 
 0.727
acta1b
Actin alpha 1, skeletal muscle b.
    
 
 0.715
gucd1
Guanylyl cyclase domain-containing 1.
      
 0.677
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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