Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nudt1Nudix (nucleoside diphosphate-linked moiety X)-type motif 1; Belongs to the Nudix hydrolase family. (156 aa)    
Predicted Functional Partners:
nudt5
Nudix (nucleoside diphosphate-linked moiety X)-type motif 5; Belongs to the Nudix hydrolase family.
   
 
 0.897
nudt18
8-oxo-dGDP phosphatase NUDT18; Mediates the hydrolysis of oxidized nucleoside diphosphate derivatives. Hydrolyzes 8-oxo-7,8-dihydroguanine (8-oxo-Gua)-containing deoxyribo- and ribonucleoside diphosphates to the monophosphates. Hydrolyzes 8-oxo-dGDP and 8-oxo-GDP with the same efficiencies. Hydrolyzes also 8-OH-dADP and 2-OH-dADP. Probably removes oxidized guanine nucleotides from both the DNA and RNA precursor pools (By similarity).
      
 0.851
nudt17
Nucleoside diphosphate-linked moiety X motif 17; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family.
      
 0.816
nudt14
Nudix (nucleoside diphosphate-linked moiety X)-type motif 14.
   
 
 0.816
nudt15
Nudix (nucleoside diphosphate-linked moiety X)-type motif 15; Belongs to the Nudix hydrolase family.
      
 0.816
nudt22
Nudix (nucleoside diphosphate-linked moiety X)-type motif 22.
   
  
 0.807
ogg1
8-oxoguanine DNA glycosylase.
   
  
 0.787
LOC100001620
Aminoacylase 1.
    
 
 0.782
acy1
Aminoacylase 1.
    
 
 0.782
nudt3a
Nudix (nucleoside diphosphate-linked moiety X)-type motif 3a.
    
 
 0.781
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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