Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mark2aNon-specific serine/threonine protein kinase. (759 aa)    
Predicted Functional Partners:
mapre1a
Microtubule-associated protein, RP/EB family, member 1a.
    
 
 0.840
esyt3
Extended synaptotagmin-like protein 3.
      
 0.814
arhgef7a
Rho guanine nucleotide exchange factor (GEF) 7a.
      
 0.773
fgfr1op
Chemokine (C-C motif) receptor 6a.
   
  
 0.739
slc12a8
Solute carrier family 12 member 8.
      
 0.736
ppp1r12c
Protein phosphatase 1, regulatory subunit 12C.
    
 
 0.727
ralgapa1
Ral GTPase-activating protein, alpha subunit 1 (catalytic).
      
 0.681
mtcl1
Microtubule crosslinking factor 1.
    
 
 0.635
macf1a
Microtubule actin crosslinking factor 1a.
   
 
 0.589
mapre1b
Microtubule-associated protein, RP/EB family, member 1b.
    
 
 0.586
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.