STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sirt5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (305 aa)    
Predicted Functional Partners:
nadsyn1
Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.
  
 
 0.942
nampta
Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.
     
 0.940
namptb
Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.
     
 0.927
nudt12
Nudix (nucleoside diphosphate-linked moiety X)-type motif 12.
    
 0.916
zgc:64002
Zgc:64002.
     
 0.905
nnt
Nicotinamide nucleotide transhydrogenase.
   
 
 0.903
nnt2
Nicotinamide nucleotide transhydrogenase 2.
   
 
 0.903
LOC101886891
Uncharacterized protein.
     
 0.902
enpp1
Ectonucleotide pyrophosphatase/phosphodiesterase 1.
    
 0.900
sirt6
Sirtuin (Silent mating type information regulation 2 homolog) 6 (S. cerevisiae).
  
 
0.850
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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