STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clcn1aChloride channel protein. (1011 aa)    
Predicted Functional Partners:
scn4ab
Sodium channel protein type 4 subunit alpha B; Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states. Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles.
   
  
 0.610
ENSDARP00000151986
Uncharacterized protein.
    
 
 0.570
atp1b2b
Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.
   
  
 0.544
dpt
Zgc:136613 protein.
   
  
 0.504
atp1a2a
Sodium/potassium-transporting ATPase subunit alpha.
      
 0.492
ostm1
Osteoclastogenesis-associated transmembrane protein 1.
   
 
 0.492
slc44a5a
Choline transporter-like protein 5-A.
      
 0.488
paplna
Papilin a, proteoglycan-like sulfated glycoprotein.
      
 0.480
arhgap21a
Rho GTPase-activating protein 21a.
   
  
 0.414
F1QXE0_DANRE
Si:ch211-173a9.6.
      
 0.405
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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