Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
chodlChondrolectin; Plays a role in the development of the nervous system such as in neurite outgrowth and elongation. Involved in motor axon growth and guidance. Required for correct interactions of motor axons with the horizontal myoseptum. (296 aa)    
Predicted Functional Partners:
tmem41b
Transmembrane protein 41B; Required for normal motor neuron development. Required for autophagosome formation (By similarity); Belongs to the TMEM41 family.
      
 0.815
NRXN2
Neurexin 2.
      
 0.771
gpbp1l1
GC-rich promoter-binding protein 1-like 1.
      
 0.668
uba1
Ubiquitin-like modifier-activating enzyme 1; Belongs to the ubiquitin-activating E1 family.
      
 0.561
KCNJ15
Potassium voltage-gated channel subfamily J member 15.
      
 0.561
nrn1a
Neuritin; Modulates postsynaptic dendritic arbor elaboration and synaptic maturation; Belongs to the neuritin family.
      
 0.552
pls3
Plastin 3 (T isoform).
      
 0.500
dop1b
DOP1 leucine zipper-like protein B.
      
 0.490
uspl1
SUMO-specific isopeptidase USPL1; SUMO-specific isopeptidase involved in protein desumoylation. Specifically binds SUMO proteins with a higher affinity for sumo2 and sumo3 which it cleaves more efficiently. Also able to process full- length SUMO proteins to their mature forms. Plays a key role in RNA polymerase-II-mediated snRNA transcription in the Cajal bodies (By similarity). Is a component of complexes that can bind to U snRNA genes (By similarity).
    
 0.486
mcm3ap
Minichromosome maintenance complex component 3-associated protein.
   
 
 0.453
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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