Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
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[Homology]
Score
abl2Tyrosine-protein kinase. (1135 aa)    
Predicted Functional Partners:
crkl
V-crk sarcoma virus CT10 oncogene homolog (Avian)-like.
    
 0.984
crk
V-crk sarcoma virus CT10 oncogene homolog (Avian).
    
 0.984
rb1
Retinoblastoma 1.
    
 0.965
abl1
Tyrosine-protein kinase.
     
  0.944
E7EZC1_DANRE
Si:ch211-168d1.3.
    
 0.914
rin1a
Ras and Rab interactor 1a.
    
 0.914
grb2b
Growth factor receptor-bound protein 2b.
    
 0.904
grb2a
Growth factor receptor-bound protein 2a.
    
 0.904
abi1b
Abl-interactor 1b.
    
 0.894
shc1
SHC (Src homology 2 domain-containing)-transforming protein 1.
    
 0.868
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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