Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fitm2Fat storage-inducing transmembrane protein 2; May play a role in the regulation of cell morphology and cytoskeletal organization (By similarity). Plays an important role in lipid droplet accumulation in liver and intestine during embryogenesis. (252 aa)    
Predicted Functional Partners:
suox
Sulfite oxidase.
     
  0.875
bscl2
BSCL2 lipid droplet biogenesis-associated, seipin.
      
 0.847
dgat2
Diacylglycerol O-acyltransferase 2; Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation (By similarity).
      
 0.755
atl1
Atlastin GTPase 1.
      
 0.737
agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta).
      
 0.713
atl2
Atlastin GTPase 2.
      
 0.678
atl3
Atlastin 3.
      
 0.639
galm
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
     
  0.609
plin3
Perilipin; Belongs to the perilipin family.
     
 0.605
luc7l3
LUC7-like 3 pre-mRNA-splicing factor.
      
 0.602
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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