STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fitm2Fat storage-inducing transmembrane protein 2; May play a role in the regulation of cell morphology and cytoskeletal organization (By similarity). Plays an important role in lipid droplet accumulation in liver and intestine during embryogenesis. (252 aa)    
Predicted Functional Partners:
bscl2
BSCL2 lipid droplet biogenesis-associated, seipin.
      
 0.849
atl1
Atlastin GTPase 1.
      
 0.753
atl2
Atlastin GTPase 2.
      
 0.683
plin3
Perilipin; Belongs to the perilipin family.
   
  
 0.673
agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta).
      
 0.654
dgat2
Diacylglycerol O-acyltransferase 2; Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation (By similarity).
      
 0.653
atl3
Atlastin 3.
   
  
 0.622
plin2
Perilipin; Belongs to the perilipin family.
   
  
 0.587
scap
SREBF chaperone.
      
 0.559
slc49a4
Solute carrier family 49 member 4.
      
 0.556
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.