Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tm7sf2Transmembrane 7 superfamily member 2. (421 aa)    
Predicted Functional Partners:
cyp51
Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.
   
 0.996
msmo1
Methylsterol monooxygenase 1; Catalyzes the first step in the removal of the two C-4 methyl groups of 4,4-dimethylzymosterol; Belongs to the sterol desaturase family.
   
 0.993
dhcr24
24-dehydrocholesterol reductase.
   
 0.993
sc5d
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 0.986
ebp
EBP cholestenol delta-isomerase.
   
 
 0.961
hsd17b7
Hydroxysteroid (17-beta) dehydrogenase 7.
   
 
 0.956
lbr
Lamin B receptor.
     
  0.950
sqlea
Squalene epoxidase a.
   
 
 0.897
nsdhl
NAD(P)-dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family.
   
 
 0.868
ERG28
Ergosterol biosynthesis 28 homolog.
   
 
 0.866
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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