Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
snapc1aSmall nuclear RNA-activating complex, polypeptide 1a. (349 aa)    
Predicted Functional Partners:
snapc4
Small nuclear RNA-activating complex, polypeptide 4.
    
 
 0.987
snapc3
Small nuclear RNA-activating complex, polypeptide 3.
    
 
 0.964
snapc5
Small nuclear RNA-activating complex, polypeptide 5.
    
 
 0.957
gtf2b
General transcription factor IIB.
    
 
 0.760
zgc:162472
Zgc:162472.
    
 
 0.673
ENSDARP00000138122
Si:ch211-204c21.1.
    
 
 0.673
arhgef7b
Rho guanine nucleotide exchange factor (GEF) 7b.
      
 0.660
tbpl2
TATA box-binding protein-like protein 2; TATA box-binding transcription factor (By similarity). Members of the TBP family are differentially required to regulate transcription and development during early embryogenesis. Commits mesoderm to the hematopoietic lineage during hemopoiesis, acting via mespa. Binds to the mespa promoter.
   
 
 0.652
polr3d
Polymerase (RNA) III (DNA directed) polypeptide D.
    
 
 0.649
polr3f
DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
   
 
 0.604
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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