Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
unm_sa1261Serine/threonine-protein kinase SBK1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (409 aa)    
Predicted Functional Partners:
tmem201
Transmembrane protein 201; May be involved in actin-dependent nuclear movement. May be involved in the organization of the nuclear envelope. May recruit Ran GTPase to the nuclear periphery; Belongs to the TMEM201 family.
      
 0.880
ENSDARP00000135796
Si:ch211-25d12.7.
      
 0.874
rgs13
Regulator of G protein-signaling 13.
   
  
 0.803
sla2
Src-like-adaptor 2.
      
 0.719
clstn1
Calsyntenin 1.
      
 0.594
cnksr3
Cnksr family member 3.
      
 0.561
gnptab
N-acetylglucosamine-1-phosphotransferase subunits alpha/beta; Catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. M6P residues are required to bind to the M6P receptors (MPR), which mediate the vesicular transport of lysosomal enzymes to the endosomal/prelysosomal compartment.
     
  0.550
p2rx4b
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
   
  
 0.437
rbm28
RNA-binding motif protein 28.
      
 0.436
myadml2
Myeloid-associated differentiation marker-like 2.
   
  
 0.435
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (16%) [HD]